Comparison of α-adrenoceptor involvement in the antinociceptive action of tizanidine and clonidine in the mouse
T Kameyama, T Nabeshima, K Matsuno… - European journal of …, 1986 - Elsevier
… , haloperidol) showed no effect on the action of tizanidine and clonidine. From these results,
it … mediating the tizanidine and clonidine antinociceptive action in the tail-flick test. Tizanidine …
it … mediating the tizanidine and clonidine antinociceptive action in the tail-flick test. Tizanidine …
α-1-Adrenergic receptor agonist activity of clinical α-adrenergic receptor agonists interferes with α-2-mediated analgesia
DW Gil, CV Cheevers, KM Kedzie… - The Journal of the …, 2009 - pubs.asahq.org
… Definition of the role of alpha receptor subtypes in alpha … , but a surprising difference
identified in the activity of the α-2 … activity of clonidine and tizanidine was a liability in wild-type …
identified in the activity of the α-2 … activity of clonidine and tizanidine was a liability in wild-type …
α‐Adrenoceptor and opioid receptor modulation of clonidine‐induced antinociception
F Sierralta, D Naquira, G Pinardi… - British journal of …, 1996 - Wiley Online Library
… A comparison of clonidine with morphine for antinociceptive … of alpha adrenoceptor antagonists
and clonidine in the … Inhibitory effects of clonidine and tizanidine on release of substance …
and clonidine in the … Inhibitory effects of clonidine and tizanidine on release of substance …
Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis
… that likely mediate the antinociceptive effects of these agents. … may play a role in the analgesic
effects of clonidine following … The key difference between clonidine and dexmedetomidine …
effects of clonidine following … The key difference between clonidine and dexmedetomidine …
The effects of clonidine and tizanidine on responses of nociceptive neurons in nucleus ventralis posterolateralis of the cat thalamus
K Hirata, N Koyama, T Minami - Anesthesia & Analgesia, 1995 - journals.lww.com
… clonidine can also produce antinociceptive effects on behavioral and spinal neuronal responses,
indicating involvement of spinal mechanisms in antinociception [… units, the difference in …
indicating involvement of spinal mechanisms in antinociception [… units, the difference in …
Centhaquin antinociception in mice is mediated by α2A-and α2B-but not α2C-adrenoceptors
… α 2 -adrenoceptors are involved in clonidine antinociception. … differences may exist between
centhaquin and clonidine in … Further, the antinociceptive effects of tizanidine are mediated …
centhaquin and clonidine in … Further, the antinociceptive effects of tizanidine are mediated …
Pharmacological analysis of α2-adrenoceptor subtypes mediating analgesic, anti-inflammatory and gastroprotective actions
… We aimed to compare the … the antinociceptive action of clonidine. These results indicate
that α 2B/2C -like adrenoceptor subtype may also be involved in this antihyperalgesic effect. …
that α 2B/2C -like adrenoceptor subtype may also be involved in this antihyperalgesic effect. …
α2-Adrenergic Agonists for Regional Anesthesia: A Clinical Review of Clonidine (1984 - 1995)
JC Eisenach, M De Kock, W Klimscha - The Journal of the American …, 1996 - pubs.asahq.org
… In the first, one can compare analgesia from an equal dose of clonidine administered by …
anesthetic alone was compared with that anesthetic and clonidine infrequently report significant …
anesthetic alone was compared with that anesthetic and clonidine infrequently report significant …
Antagonists of adenosine and alpha-2-adrenoceptors reverse the anticonvulsant effects of tizanidine in DBA/2 mice
GB De Sarro, A De Sarro - Neuropharmacology, 1989 - Elsevier
… Significant differences between groups treated with tizanidine alone or in associaxion with …
protective effects of tizanidine and perhaps of other alphaadrenoceptor agonists (ie clonidine) …
protective effects of tizanidine and perhaps of other alphaadrenoceptor agonists (ie clonidine) …
Meperidine Exerts Agonist Activity at the α2B-Adrenoceptor Subtype
K Takada, DJ Clark, MF Davies, PH Tonner… - The Journal of the …, 2002 - pubs.asahq.org
… hind-paw licking when compared with saline-injected animals. … the antinociceptive effects
of clonidine in mice when using … MR: Inhibitory effects of clonidine and tizanidine on release of …
of clonidine in mice when using … MR: Inhibitory effects of clonidine and tizanidine on release of …